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This is also how Jido AI plugs in. The ReAct, Chain-of-Thought, and other reasoning strategies are just strategy implementations that add LLM calls to the loop. Same cmd/2 contract, same directive system, same agent. The AI layer is an extension, not a separate world.

Klenerman and Balasubramanian’s great insight was that template DNA could be sequenced by synthesizing a complementary strand of reversible terminators; basically, extending the chain one base at a time and determining the identity of each nucleotide by looking at the color of its fluorophore. In 1998, the pair started a company called Solexa to develop the technology.

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